Type 1 diabetes mellitus (DMT1) is characterized by the destruction of pancreatic beta cells caused by an autoimmune process that usually leads to the absolute lack of insulin.

AXA Diagnostics offers a wide range of ELISA kits that allow to detect, in peripheral blood, the specific autoantibodies in order to study the autoimmune process activation against pancreatic beta cells.

The most important markers that allow both to groped a prediction of the disease and to diagnose it are anti-islet cell antibodies IA-2, code AXIAE, anti-insulin antibodies Anti-Insulin, code 8020E, anti-glutamic acid decarboxylase antibodies GAD₆₅, code AXGDE and anti-ZnT8 antibodies ZnT8, code AXZnT8/96.

The anti-ZnT8 antibodies represent a predictive marker for the rapid progression of the disease as they precede the onset of type 1 diabetes clinical symptoms.